In another case, a 4,025 bp deletion (CADD-SV score: 21.3) removed three exons of TARS2 in a participant with chronic kidney disease, consistent with prior studies linking TARS2 mutations to this condition74 (Supplementary Fig. 8g,h, Supplementary Tables 3 and 4). The gene discussed is TARS2; the disease is chronic kidney disease.