We identified multiple DETs in AD (Supplementary Table 6), including both known and novel isoforms (Fig. 5a), and four isoforms that were significantly switched for GTPBP6, LUC7L2, STX7, and SEPTIN4 (Fig. 5b–e; Supplementary Table 7). The gene discussed is GTPBP6; the disease is Alzheimer disease.