TNF and rheumatoid arthritis: KEGG analysis indicated enrichment in pathways, including the NOD-like receptor (NLR) signaling pathway, coronavirus disease (COVID-19), intestinal immune network for IgA production, Toll-like receptor (TLR) signaling pathway, chemokine signaling pathway, rheumatoid arthritis, IL-17 signaling pathway, TNF signaling pathway, and necroptosis (Figure 3B).