In the study by Barbara Klein et al., hMSC-SB623 cell treatment for focal ischemic stroke in rats show that hMSC-SB623 cell treatment significantly enhanced GFAP expression in the ipsilesional cortex and corpus callosum, as well as in the peri-stroke region and increases proliferation of GFAP + astrocytes. The gene discussed is GFAP; the disease is stroke disorder.