TGFB1 and neoplasm: Similarly, in human umbilical cord-derived MSCs (hUC-MSCs), transfection with miR-3940-5p mimics led to EVs that suppressed EMT, invasion, metastasis, and tumor progression by targeting integrin subunit alpha 6 (ITGA6) and inhibiting the transforming growth factor beta 1(TGF-β1) pathway [40].