Tumor marker analysis revealed cytokeratin 19 fragment antigen 21 − 1 (CYFRA21-1) 17.17ng/ml (reference value 0–3.3ng/ml), neuron-specific enolase (NSE) 20.34ng/ml (reference value 0–16.3ng/ml), carcinoembryonic antigen (CEA) 8.29ng/ml (reference value < 5ng/ml), and squamous cell carcinoma (SCC) 2.920ng/ml (reference value 0–2.7ng/ml). This evidence concerns the gene ENO2 and neoplasm.