PYCR1 and non-small cell lung carcinoma: Based on the differential magnitude (ΔMag) of the average normalized PYCR1 signal values between the lung tumor tissues and matched lung normal tissues, patients with NSCLC were categorized into two groups: PYCR1-upregulated (PYCR1up) and PYCR1-downregulated (PYCR1down) (Fig. 1a and Supplementary Table 1).