Over the past decade cpb2 gene has been associated with a possible role in enteric diseases affecting a wide range of food-producing and wild animals56–58 and human59,60 Although it is not used for toxinotyping and its significance in many species remains unclear, its presence has been associated with cases of diarrhea in animals and may enhance virulence in co-infection scenarios61. The gene discussed is CPB2; the disease is coinfection.