On comparing CF and non-CF children, salivary biochemical markers showed a significant increase in α-Amylase (p < 0.001), TNF-α (p < 0.001), and IL-6 (p < 0.001), and a significant decrease in SOD (p = 0.027) and catalase (p < 0.001). The gene discussed is IL6; the disease is cystic fibrosis.