The high frequency of LRRK2 p.G2385R and p.R1628P variants in Malaysia should be considered when broadening the recruitment of participants for studies of LRRK2, since such underrepresented populations with enriched cases of “genetic PD” may also be able to host, and benefit from, genetics-targeted biomarker and therapeutic programs. The gene discussed is LRRK2; the disease is Parkinson disease.