We also observed enrichment in pathways associated with circadian entrainment (e.g., GNG11, GUCY1B1) and hypertrophic cardiomyopathy (e.g., ITGB3, ITGA2B, IL6), suggesting systemic disruptions in PitNET PBMCs (Fig. 1e). Here, IL6 is linked to hypertrophic cardiomyopathy.