We also observed enrichment in pathways associated with circadian entrainment (e.g., GNG11, GUCY1B1) and hypertrophic cardiomyopathy (e.g., ITGB3, ITGA2B, IL6), suggesting systemic disruptions in PitNET PBMCs (Fig. 1e). The gene discussed is GNG11; the disease is hypertrophic cardiomyopathy.