Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis highlighted detectable enrichment in several critical signaling pathways, including the PI3K-Akt signaling pathway, GMP-PKG signaling pathway, proteoglycans in cancer, cytokine-cytokine receptor interaction, inflammatory mediator regulation of TRP channels, axon guidance, and gap junctions (Fig. 9f–h). This evidence concerns the gene AKT1 and cancer.