The aetiology of sarcoidosis remains unclear, where genetic variants (eg, HLA-DRB1*1101; ANXA11)2 3 and environmental exposure (eg, silica, metal dusts)4 are implicated in disease progress.5, 7 The annual incidence of sarcoidosis varies across continents, ranging from 1 to 15 per 100 000 people. This evidence concerns the gene HLA-DRB1 and sarcoidosis.