RPS6KB1 and neoplasm: We showed that temporal activation of S6K (S6KCA) or Rag (RagACA) in BBB glia were sufficient to induce a smaller reduction in glial number and tumor size upon NR compared to the mCherryRi control (Fig 7H–7J, the number of glia and tumor size are reduced by 54% and 65%, respectively, upon NR in mCherryRi, by 20% and 30% in RagCA, and by 38% and 36% in S6KCA,statistical assessment described in Materials and methods).