Rs118039278 (6q25.3, LPA locus), rs1537372 (again 9p21.3, CDKN2B-AS1 locus), rs4722172 (7p15.3, IL6-locus) and rs6025 (1q24.2, Factor V Leiden locus) are all PAD-associated SNPs previously reported in a large population study (the Million Veteran Program with replication in the UK Biobank, [3]). This evidence concerns the gene F5 and peripheral arterial disease.