CD47 and breast neoplasm: 2022). CD47 is known to be abundant on EVs from a wide variety of cell sources, such as mesenchymal stem cells and breast tumour cells (Xu et al. 2023; Kugeratski et al. 2021). CD47 plays a key role in immune evasion by interaction with its ligand, signal‐regulatory protein (SIRP) α (van Duijn et al. 2022).