TARDBP and amyotrophic lateral sclerosis: Despite the complex and diverse genetic and molecular aetiology, approximately 97% of ALS cases display TDP‐43 pathology, characterised by the mislocalisation and aggregation of hyper‐phosphorylated TDP‐43 (pTDP‐43) inclusions in the cytoplasm of neurons (Mackenzie et al. 2010; Mackenzie 2007; Trist et al. 2022; Chen and Cohen 2019; McGurk et al. 2020).