Over 30 different gene mutations are implicated in the aetiology of ALS, including mutations in genes encoding guanine nucleotide exchange chromosome 9 open reading frame 72 (C9ORF72), Cu/Zn superoxide dismutase 1 (SOD1) RNA‐binding protein Fused in Sarcoma (FUS) and TAR DNA‐binding protein 43 (TDP43). This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.