CRP and infection: In the present study, the CRP and ESR provided acceptable diagnostic performance, with an AUC of 0.934 for CRP (0.898 sensitivity, 0.853 specificity) at a cutoff of 10.95 mg/L, and for ESR an AUC of 0.832 (0.739 sensitivity, 0.833 specificity) at a cutoff of 36.5 mm/h.The references provided by the Musculoskeletal Infection Society (MSIS), the Infectious Diseases Society of America (IDSA), and the International Consensus Meeting (ICM) for the diagnosis of PJI are CRP > 10 mg/L; ESR > 30 mm/h (Sousa et al., 2023).