Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells, role in immune response, inflammation, cell adhesion and chemotaxis Salmonella infection mediates migration of dendritic cells into the intestinal lumen via CX3CR1.CX3CR1 + Cell-Mediated Salmonella Exclusion Protects the Intestinal Mucosa during the Initial Stage of Infection.CX3CR1 + macrophage subsets recruit and activate CD4 + T and B cells to the sites of Salmonella invasion. Here, CD4 is linked to infection.