We identified 21 proteins associated with DLB after multiple test correction, including MSLN (β = 0.292; FDR-adjusted p = 3.93 × 10−2) and SAA1 (β = 0.360; FDR-adjusted p = 8.07 × 10−3) that were associated exclusively with DLB. Here, MSLN is linked to Lewy body dementia.