In addition, compared with the WT group, mice in the AD group had significantly decreased autophagy initiation markers Beclin1 and the LC3‐II/I ratio in the hippocampal CA1 region, as well as raised P62 protein levels; AET increased Beclin1 and the LC3‐II/I ratio and decreased the P62 protein level (Figure 3, all p < 0.01). Here, MAP1LC3A is linked to Alzheimer disease.