ELISA revealed that mice in the AD group displayed elevated levels of inflammatory cytokines IL‐1β and IL‐18 relative to those in the WT group; yet, AET diminished the levels of IL‐1β and IL‐18 in the hippocampal CA1 region of AD mice (Figure 1E, both p < 0.01). This evidence concerns the gene IL18 and Alzheimer disease.