To explore whether AET exerts its effects through the ERS‐autophagy pathway, we further examined the expression of ERS‐related genes GRP78/Bip, ATF4, and CHOP, as well as autophagy‐related genes Beclin1, LC3‐II, LC3‐I, and P62 in the hippocampal CA1 region of AD mice by Western blot. This evidence concerns the gene DDIT3 and Alzheimer disease.