XBP1 and neoplasm: To understand the effect of targeted deletion of XBP1 on KPC tumor-induced muscle atrophy, we next generated transverse sections of TA (fast/glycolytic) and soleus (slow/oxidative) muscle, performed anti-laminin and DAPI staining or H&E staining, followed by morphometric analysis (Figs. 2G–N and  EV2C–E).