We utilized qRT-PCR to validate increased expression of various transcripts related to the IRE1α/XBP1 arm of the UPR, such as IRE1 (gene name: Ern1), Xbp1, Dnajb9, Edem1, and CHOP (gene name: Ddit3) in GA muscle of KPC tumor-bearing mice compared to control mice. The gene discussed is EDEM1; the disease is neoplasm.