Similarly, during bacterial infection, CaMKKβ inhibition impaired the expansion of lymphocytes (Appendix Fig. S6E) and T cells (Appendix Fig. S6F–H), reduced the proportion of T cells producing IL-2 (Appendix Fig. S7A,B) or expressing CD122 (Appendix Fig. S7C), and exacerbated A. hydrophila-induced T-cell apoptosis (Appendix Fig. S7D,E). The gene discussed is CAMKK2; the disease is bacterial infectious disease.