CXCL10 and lupus nephritis: Furthermore, C3-LHF1 potentiated tumor necrosis factor (TNF)-induced C-X-C motif chemokine ligand 10 (CXCL10) secretion and decreased markers of healthy podocytes, suggesting a role in podocyte injury and inflammatory tissue remodeling characteristic of lupus nephritis (Weinstein et al, 2021).