This subnetwork included the 34 protein products of the 12 canonical AOM‐related genes (Fmd, Fpo/Fqo, Ftr, HdrABC, HdrDE, Mch, Mcr, Mer, MHC, Mtd, Mtr and Rnf) plus their immediate neighbours in the full PPI network (total 474 proteins). The gene discussed is HLA-C; the disease is infectious otitis media.