THY1 and posterior cortical atrophy: As a member of the Thy-1/Ly-6 family involved in cell adhesion and metastasis, PSCA’s overexpression in high-grade PCa and metastatic lesions underscores the therapeutic potential of PSCA inhibitors in targeting tumor-stroma crosstalk to prevent metastatic spread (Nayerpour Dizaj et al., 2024).