HSPB1 and posterior cortical atrophy: Furthermore, HSPB1, a molecular chaperone implicated in apoptosis evasion and chemotherapy resistance (Garrido et al., 2006; Hadaschik et al., 2008; Kamada et al., 2007), aligns with the observed enrichment of survival pathways in aggressive PCa (Shiota et al., 2013; Vasiljević et al., 2013).