CRP and HIV infectious disease: Importantly, chronic HIV infection leads to detrimental chronic immune activation and inflammation (e.g. elevated IL-6, scCD14, sCD163, C-reactive protein [CRP], etc.), even after decades of suppressive antiretroviral therapy (ART), and people with HIV continue to have elevated risks of various cardiopulmonary, metabolic, and oncological diseases over time due to ongoing persistent inflammation (Borges et al., 2013; Sereti et al., 2017; Nordell et al., 2014; Tenorio et al., 2014; Kuller et al., 2008).