These concerns are justified, since SARS-CoV-2 infection may induce lymphopenia (Shariq et al., 2022) and, in particular, as mentioned above , reduce the pool of M. tuberculosis-specific CD4+ T cells (Riou et al., 2021), which are central to immune control of M. tuberculosis infection (Flynn and Chan, 2022). The gene discussed is CD4; the disease is lymphopenia.