RC3H1 and precursor B-cell acute lymphoblastic leukemia: Our analysis revealed that expression levels of MBNL1, PCBP2, RC3H1, and SRSF2 is significantly elevated in B-ALL patients exhibiting any alteration (such as mutations, truncations, copy number variations) in these RBPs compared to patients with no alterations (Supplementary Fig. 3a-3d).