On the other hand, in Brazil, the incidence of hypertension was higher in APSGN groups than in control groups after 10 years of follow-up in children with APSGN, but there was no discernible difference in the assessment of renal function, which includes serum creatinine, cystatin C, eGFR, albuminuria, and hematuria [27]. In Hoy et al.'s study [25], children with a history of APSGN five years prior had more proteinuria and poorer glomerular filtration rates. The gene discussed is CST3; the disease is Hypertension.