F8 and hemophilia: Reasons for exclusion were ongoing ITI (n = 6), cumulative number of FVIII exposure days at inhibitor developed exceeding 150 days (n = 4), treatment regimen not fulfilling ITI definition (n = 3), duplicate patient inclusion (n = 2), poor quality DNA sample (n = 2), unknown hemophilia severity (n = 2), and non-SHA (n = 1) (Figure).