To further understand the relationship between exosomal miR-122-5p and liver injury and cholestasis in patients with PBC and its diagnostic value, Pearson’s correlation analysis was performed, which showed that the level of exosomal miR-122-5p was positively correlated with alanine aminotransferase (ALT), aspartate aminotransferase (AST), direct bilirubin (DBIL), γ-glutamyl transpeptidase (γ-GT), alkaline phosphatase (ALP), and total bile acid (TBA) (p<0.05), but had no correlation with albumin (ALB), total bilirubin (TBIL), and indirect bilirubin (IBIL) (Figure 1). The gene discussed is ALB; the disease is cholestasis.