FBG, insulin, HbA1c, homeostasis model assessment of insulin resistance (HOMO-IR), low-density lipoprotein cholesterol (LDL-c), total cholesterol (CHOL), LDL.HDL ratio, atherogenic index of plasma (AIP), malondialdehyde (MDA), IL-6 ↓; quantitative insulin sensitivity check index (QUICKI), HDL-c, total antioxidant capacity (TAC) ↑. The gene discussed is INS; the disease is Insulin resistance.