MTAP and cancer: To elucidate the molecular mechanisms by which MTAP regulates antitumor immune responses, we performed bulk RNA sequencing to analyze transcriptomic alterations in MTAP-WT (WT) and MTAP-KO (KO) cancer cells co-cultured with peripheral blood mononuclear cells (PBMCs) (WT+PBMC and KO+PBMC).