Apart from the above facts, it was found that in the postmortem frontal brain of people with ASD, both RORA and aromatase proteins are significantly lower than in controls; a correlation coefficient of 0.91 indicates that there may be a causative link between RORA decrease and aromatase deficiency (Sarachana et al., 2011). This evidence concerns the gene CYP19A1 and aromatase deficiency.