Patients with the highest APAR had more tendency to be older, suffering from heart failure, diabetes, and CKD, and exhibiting higher levels of WBC, platelet, PT, INR, ALT, AST, creatinine, BUN, potassium, lactate, anion gap, and SOFA score, as well as lower hemoglobin, PO2, sodium, and BE. This evidence concerns the gene GPT and chronic kidney disease.