Additionally, β-CD-NSs-camptothecin suppressed the production of β-PIX, a member of the Rho family of activators, migration, phosphorylation of the Erk1/2 MAPK, adherence of tumor cells to vascular endothelial cells, and the secretion of pro-angiogenic molecules (VEGF-α and IL-8) (Gigliotti et al., 2017). The gene discussed is VEGFA; the disease is neoplasm.