PMEL and neoplasm: Immunohistochemistry revealed one immunophenotype with nuclear punctate positivity for CK (Figure 5)/CK20 (Figure 6), two immunophenotypes with CK/CK20 negativity, similar residual immunophenotype, along with tumor cells that were EMA positive, CD56 positive (Figure 7), Syn positive, β-catenin membrane positive, p40, LCA, CD99, S100, HMB-45, SOX-10, TTF-1, CDX-2, and CD34 negative.