Dr. Darko Bosnakovski (University of Minnesota, Minnesota, United States) demonstrated the metalloproteases (MMPs) were the culprit in Facioscapulohumeral muscular dystrophy (FSHD), by using a Dux4 overexpression mouse model to mimic the FSHD. Here, DUX4 is linked to facioscapulohumeral muscular dystrophy.