FN1 and colorectal carcinoma: Prior to this study, most of the experiments used other subspecies of Fn such as Fn subspecies nucleatum (Fnn) ATCC 25586 and Fnn ATCC 23726 as model organisms (Zepeda-Rivera et al., 2024), and their implication in CRC development as well as progression was observed in multiple studies (Abed et al., 2016; Yu et al., 2017; Zepeda-Rivera et al., 2024).