SEZ6 and early-onset autosomal dominant Alzheimer disease: Two RNAs were shared between the two regions, Thy1 and Sez6. Thy1 is a cell surface glycoprotein that functions in cell-to-cell communication (Hu et al., 2022) and Sez6 encodes a protein altered in Alzheimer’s disease patient’s cerebral spinal fluid and important in neuronal signaling (Munro et al., 2016).