The selected predictors included clinical and demographic variables such as alcohol consumption, urine cytology, history of prior surgery, duration of smoking and drinking, and blood pressure, as well as histopathological features (e.g., vascular and perineural invasion, tumor stage and grade) and molecular markers (e.g., Uroplakin III, GATA3, CK20, AR, PD-L1, and HER2 expression). This evidence concerns the gene CD274 and neoplasm.