TNF and cancer: Meanwhile, the core targets were subjected to the KEGG pathway enrichment analysis to screen for pathways with q<0.05, and a total of twenty were obtained, such as the MicroRNAs in cancer, the Neurotrophin signaling pathway, the mTOR signaling pathway, the TNF signaling pathway, the Rap1 signaling pathway, and the MAPK signaling pathway, the Insulin signaling pathway, the Hippo signaling pathway, the FoxO signaling pathway (Supplementary Figure S3).