According to studies by Kawagoe et al. (2020) and Tian et al. (2020), GC tissues have much higher levels of SERPINH1 protein and mRNA expression than normal tissues, and inhibiting SERPINH1 dramatically reduced the potential of cancer cells to migrate and invade (Kawagoe et al., 2020; Tian et al., 2020). The gene discussed is SERPINH1; the disease is cancer.