One month before admission, routine follow-up revealed the onset of NS (4 + proteinuria, 24 h UTP 10.93 g/d, serum albumin 23.2 g/L, LDL-C 8.76 mmol/L) with acute kidney injury (AKI) (serum creatinine 138.2 μmol/L) and radiographic disease progression. This evidence concerns the gene ALB and acute kidney injury.