scRNA-seq of P7 BC progenies confirmed these bulk sequencing findings, showing a reduction in important BC genes, including Prkca (which encodes PKC), Vsx2, Trpm1, Pcp2, as well as Cabp5, Insm1, and Gag1, in the cKO BC population (Figures 6N and S3B). Here, TRPM1 is linked to breast cancer.