RPS28 and hepatocellular carcinoma: In an in vivo hepatocellular carcinoma model, LeuCAG3′tsRNA was shown to enhance the translation of ribosomal protein S28 (RPS28) mRNA, promoting cell proliferation, whereas its inhibition reduced RPS28 expression, impaired ribosome assembly, and induced apoptosis (Kim et al., 2017) (Fig. 2).