In the TH-MYCN transgenic mouse model, 9 of these miRNAs, including hsa-let-7a-5p, hsa-let-7b-5p, and hsa-miR-29a-3p, were expressed at low levels in tumor tissues, suggesting that MYCN maintains its high expression by inhibiting these miRNAs (Beckers et al., 2015a). Here, MYCN is linked to neoplasm.