By binding to the promoter of the CDH1 (E‐cadherin) gene, SNAIL1, SNAIL2, and ZEB2 suppress CDH1 expression and increase CDH2 (N‐cadherin) levels, reducing cell adhesion and promoting mesenchymal traits such as increased motility and invasion in cancer cells [54, 56, 57]. This evidence concerns the gene SNAI2 and cancer.