Comparison of baseline characteristics indicated that exposure 1, exposure 2, age, sex, eGFR, ALB, urea, TCO2, AST, ALT, etiology, with hypertension, with diabetes mellitus, with anemia, use of calcium supplements, and use of diuretics were statistically significant between trajectories in both GBTM models of Hb and HCT (p<0.05) (Supplementary Data Sheet 4). This evidence concerns the gene ALB and Hypertension.