In conclusion, we identify a candidate angiogenesis related RNA panel FZD5, GTF2I mRNAs, hsa-miR-1976, and the lncRNA LINC02210 that is associated with T2DM complicated by IHD and shows concordance with serum clinical measures reflecting the transition from T2DM to T2DM+IHD. The gene discussed is GTF2I; the disease is myocardial ischemia.